Absorption

In mammals, trichloroethylene absorption may occur after inhalation, ingestion or skin exposure. Intraperitoneal uptake has been reported in experimental animals (IPCS, 1985).

In a study of five male volunteers inhaling trichloroethylene at a concentration of 70 ppm for 4 hours on 5 consecutive days, the uptake of trichloroethylene was calculated as 6.6 ± 0.4 mg/kg lean body mass in 4 hours. The trichloroethylene concentration in blood and exhaled air 18 hours after the fifth exposure, was twice as high as the concentration 18 hours after the first exposure (Monster et al., 1979). The relatively high and almost constant absorption per minute of trichloroethylene is explained by the relatively high partition coefficient between blood and air (Monster, 1979).

Trichloroethylene is readily absorbed across the skin but, in industrial situations, skin exposure is likely to be limited by the irritant nature of trichloroethylene on the skin (Sato and Nakajima, 1978).

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

Get My Free Ebook


Post a comment