Acute exposure

Inhalation

The victim should be removed from exposure and all contaminated clothing removed. The respiratory function should be assessed. Further treatment is symptomatic and supportive. See below for management of systemic effects.

Dermal

Contaminated clothing should be removed and the skin thoroughly irrigated with water or saline. Further treatment is symptomatic and supportive. See below for management of systemic effects.

The eyes should be thoroughly irrigated with water or saline for 15 minutes and then stained with fluorescein. Referral to an ophthalmologist is recommended if there is any uptake of fluorescein.

Toxicology of Solvents Ingestion

Gastric lavage may be considered if ingestion was recent, however, because of the risk of aspiration a cuffed endotracheal tube must be used to protect the airway. Activated charcoal is unlikely to be of benefit. If there has been any vomiting, coughing or wheezing then the patient will need to be assessed to see if aspiration has occurred. Treatment is supportive. See below for management of systemic effects.

Systemic effects

Monitor ECG, vital signs, and fluid and electrolyte status. Baseline liver function tests and renal function should be determined. Symptomatic and supportive. Neurological follow-up may be required.

Antidotes

There is no specific antidote for carbon disulphide.

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