Chronic exposure


As methanol is eliminated from the body relatively slowly, there is a possibility of cumulative toxicity with repeated exposures. However, there is limited information in the literature on chronic methanol exposure. Workers exposed to an average methanol concentration of 459 ppm complained of eye and nose irritation, headache, forgetfulness at work and increased sensitivity of the skin (Kawai et al., 1991).


Repeated skin exposure to methanol may cause contact dermatitis (Bevan, 2001). Eye

Delayed light reflex was reported in two methanol exposed workers with previously good vision. Another worker from the same group exhibited slight mydriasis (Kawai et al., 1991).

Toxicology of Solvents Ingestion

There is no information in the literature on the effects of chronic methanol ingestion.

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