Distribution

The concentration in blood correlates with the exposure concentration (Hjelm et al., 1990). In two individuals who died after exposure to a mixture of solvents including MIBK, the range of MIBK in tissues and body fluids was 1.4-2.5 and 0.2-0.8 mg/kg, respectively. The former worker had died after a fall into the water storage tank that was being spray painted, the concentration was highest in the vitreous humour, liver and lung tissue. The other was removed from the exposure but died nine hours later, the highest concentration was in the liver. Thus, the distribution of MIBK was different in the two workers (Bellanca et al., 1982).

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