Metabolism

The metabolism of carbon tetrachloride has not been studied in man (Baselt, 2000). Metabolism of carbon tetrachloride is primarily in the liver but many other organs have been shown to metabolise it. In the liver the route is thought to be NADPH-dependent cytochrome P450 isoenzyme reductive dehalogenation with formation of a trichloromethyl free radical, and a number of other reactions to form products such as carbon dioxide, carbon monoxide, hexachloroethane, chloroform and phosgene. Metabolism is thought to be dose-dependent and saturable, and to involve destruction of the cytochrome P450 during the metabolism process (Reid, 2001).

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

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