Akesson B, Jönsson BAG. 1997 Major metabolic pathway for N-methyl-2-pyrrolidone in humans. Drug Metab Dispos 25 (2):267-269.

Akesson B, Jönsson BAG. 2000 Biological monitoring of N-methyl-2-pyrrolidone using 5-hydroxy-N-methyl-2-pyrrolidone in plasma and urine as the biomarker. Scand J Work Environ Health 26 (3):213-218.

Akesson B, Paulsson K. 1997 Experimental exposure of male volunteers to N-methyl-2-pyrrolidone (NMP): acute effects and pharmacokinetics of NMP in plasma and urine. Occup Environ Med 54:236-240.

Akhter SA, Barry BW. 1985 Absorption through human skin of ibuprofen and flurbiprofen; effect of dose variation, deposited drug films, occlusion and the penetration enhancer N-methyl-2-pyrrolidone. J Pharm Pharmacol 37:27-37.

Barry BW, Bennett SL. 1987 Effects of penetration enhancers on the permeation of mannitol, hydrocortisone and progesterone through human skin. J Pharm Pharmacol 39:535-546.

Beaulieu HJ, Schmerber KR. 1991 M-PyrolTM (NMP) use in the microelectronics industry. Appl Occup Environ Hyg 6 (10):874-880.

Becci PJ, Knickerbocker MJ, Reagan EL, Parent RA, Burnette LW. 1982 Teratogenicity study of N-methylpyrrolidone after dermal application to Sprague-Dawley rats. Fundam Appl Toxicol 2:73-76.

Briggs GG, Freeman RK, Yaffe SJ. 1994 A Reference Guide To Fetal And Neonatal Risk. Drugs In Pregnancy And Lactation, fourth edition. Williams and Wilkins, Baltimore, Maryland.

Hass U, Jakobsen BM, Lund SP. 1995 Developmental toxicity of inhaled N-methylpyrrolidone in the rat. Pharmacol Toxicol 76:406-409.

Hass U, Lund SP, Elsner J. 1994 Effects of prenatal exposure to N-methylpyrrolidone on postnatal development and behaviour in rats. Neurotoxicol Teratol 16 (3):241-249.

Horning MG, Stratton C, Nowlin J, Harvey DJ, Hill RM. 1973 Metabolism of 2-ethyl-2-methylsuccinimide (ethosuximide) in the rat and human. Drug Metab Dispos 1 (3):569-576.

Jönsson BAG, Akesson B. 1997a Determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in human urine. J Chromatogr B 694:351-357.

Jönsson BAG, Akesson B. 1997b Determination of N-methylsuccinimide and 2-hydroxy-N-methylsuccinimide in human urine and plasma. J Chromatogr B 704:151-158.

Kuhnz W, Koch S, Jakob S, Hartmann A, Helge H, Nau H. 1984 Ethosuximide in epileptic women during pregnancy and lactation period. Placental transfer, serum concentrations in nursed infants and clinical status. Br J Clin Pharmacol 18:671-677.

Lee KP, Chromey NC, Culik R, Barnes JR, Schneider PW. 1987 Toxicity of N-methyl-2-pyrrolidone (NMP): Teratogenic, subchronic, and two-year inhalation studies. Fundam Appl Toxicol 9:222-235.

Leira HL, Tiltnes A, Svendsen K, Vetlesen L. 1992 Irritant cutaneous reactions to N-methyl-2-pyrrolidone (NMP). Contact Dermatitis 27:148-150.

Mallow DW, Herrick MK, Gathman G. 1980 Fetal exposure to anticonvulsant drugs. Arch Pathol Lab Med 104:215-218.

Mayer VW, Goin CJ, Taylor-Mayer RE. 1988 Aneuploidy induction in Saccharomyces cerevisiae by two solvent compounds, 1-methyl-2-pyrrolidinone and 2-pyrrolidinone. Environ Mol Mutagen 11 (1):31-40.

Midgely I, Hood AJ, Chasseaud LF, Brindley CJ, Baugham S, Allan G. 1992 Percutaneous absorption of co-administered N-methyl-2-[14C]pyrrolidinone and 2-[14C]pyrrolidinone in the rat. Fd Chem Toxicol 30 (1):57-64.

Solomon GM, Morse EP, Garbo MJ, Milton DK. 1996 Stillbirth after occupational exposure to N-methyl-2-pyrrolidone. J Occup Environ Med 38 (7):705-713.

Solomon HM, Burgess BA, Kennedy GL Jr, Staples RE. 1995 1-Methyl-2-pyrrolidone (NMP): reproductive and developmental toxicity study by inhalation in the rat. Drug Chem Toxicol 18 (4):271-293.

Ursin C, Hansen CM, Van Dyk JW, Jensen PO, Christensen IJ, Ebbehoej J. 1995 Permeability of commercial solvents through living human skin. Am Ind Hyg Assoc J 56:651-660.

Wells DA, Digenis GA. 1988 Disposition and metabolism of double-labeled [3H and 14C] N-methyl-2-pyrrolidinone in the rat. Drug Metab Dispos 16 (2):243-249.

Wells DA, Hawi AA, Digenis GA. 1992 Isolation and identification of the major urinary metabolite of N-methylpyrrolidinone in the rat. Drug Metab Dispos 20 (1):124-126

Wells DA, Thomas HF, Digenis GA. 1988 Mutagenicity and cytotoxicity of N-methyl-2-pyrrolidinone and 4-(methylamino)butanoic acid in the Salmonella/microsome assay. J Appl Toxicol 8 (2):135-139.

Zellers ET, Sulewski R. 1993 Modeling the temperature dependence of N-methylpyrrolidone permeation through butyl- and natural-rubber gloves. Am Ind Hyg Assoc J 54 (9):465-479.

Zimmermann FK, Scheel I, Resnick MA. 1989 Induction of chromosome loss by mixtures of organic solvents including neurotoxins. Mutat Res 224:287-303.

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