Risk Groups

Exposure to glycol ethers has been shown to be associated with adverse haematological effects. Consequently, individuals predisposed to haematological anaemia by disorders such as hereditary spherocytosis, glucose-6-phosphate dehydrogenase deficiency and sickle cell anaemia, may be at greater risk of haematological toxicity if exposed to these chemicals (Ghanayem, 1989). In addition, Cullen et al. (1992) found an association between ethnic group and haematological effects in exposed workers. Black workers, in particular, were found to have marginally low haemoglobin concentrations and total granulocyte counts. Although the study numbers were small, the difference was large and the association very strong.

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