Toxicity is due to metabolites rather than carbon tetrachloride itself Acute exposure may result in rapid central nervous system depression
Carbon tetrachloride is a potent hepatotoxin which can produce potentially fatal hepatorenal damage following ingestion, inhalation or dermal exposure
Symptoms of hepatic and/or renal toxicity may be delayed in onset for several days
Sensitisation of the myocardium to catecholamines can occur and at high concentrations sudden death can occur from cardiac arrest
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