• Relatively low acute toxicity; causes mild irritation and CNS depression

• Chronic exposure may result in peripheral polyneuropathy, characteristically distal, symmetrical sensiomotor polyneuropathy

• Neurotoxicity is due to the main metabolite (2,5-hexanedione, a y-diketone compound) and not methyl n-butyl ketone itself

• Insidious onset of clinical effects; there is deterioration after removal from exposure before gradual improvement

• Neurotoxicity usually has a good outcome depending on severity, but recovery may be slow

• Co-exposure to other solvents (e.g., methyl ethyl ketone) potentiates the toxicity of methyl n-butyl ketone

• There is limited information on the carcinogenicity, gentoxicity and reproductive toxicity of methyl n-butyl ketone

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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