Citrinin [CAS number: 518-75-2] was first isolated as a pure compound from a culture of Penicillium citrinum in 1931 [28]. Later, yellowish coloured rice imported from Thailand to Japan in 1951 was found to be contaminated with P. citrinum and subsequent investigations showed that isolates of the fungus produced citrinin. Citrinin is a mycotoxin, which is produced by A. ochraceus, P. citrinum, and related species, which contaminate grain. It causes nephropathy in livestock and has been implicated as a cause of Balkan nephropathy in humans. It frequently co-occurs with OTA with which it showed a documented synergistic effect [29,30].

0 0

Post a comment