Radioimmunoassays RIAs

The development of practical immunoassays began in the 1960s with the application of radioimmunoassays (RIAs). RIAs utilize radioactive isotopes as a label, and the amount of radioactivity measured is indicative of the amount of analyte present. RIAs are still used today, particularly for detection of very low quantities of analytes. However, due to the inherent complications of handling and disposing of radioactive materials, RIAs are less often used in the laboratory than other types of immunoassays, such as enzyme-based immunoassays (EIAs).

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