Technological Tools and Design of New Chemical Processes

Abstract Although their impact on enantioselectivity is rather limited, technological tools can provide increased productivity with simultaneous energy and time savings. Under microwave irradiation as non-conventional heating source marked rate acceleration has been evidenced in many cases and continuous-flow reactors, among which microreactors display unique features in fast heat and mass exchange, have led to more prolonged catalyst life, reduction of solvent waste and simplification of workup procedures. In the context of the design of new chemical processes, multicomponent reactions or cascade sequences offer high potentiality in the construction of complex molecules from simple precursors in a single step, so avoiding the costly protection/deprotection procedures and purification of intermediates.

Keywords Microwave-assisted synthesis Continuous-flow reactors Microreactors Cascade reactions Multicatalyst systems

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