Green Chemistry Guide

Beginning in early 1996, the EHS Product Stewardship Team began to investigate what "green" or "clean" chemistry and/or technology meant in the context of GSK. Given the many different definitions and the general focus on large petrochemical and chemical processes, there was very little information or interest available to help our investigations. We undertook a systematic evaluation of a few GSK chemical processes, and evaluated these processes using a variety of metrics. Work with the American Institute of Chemical Engineers Center for Waste Reduction Technologies helped to narrow the scope and a reduced metrics set, discussed in Section 6.1.2 of this book, was chosen for application to about 250 individual chemical syntheses. From an extended and extensive evaluation of the data, a considerable amount of very useful information was obtained (Curzons et al., 2001) and eventually converted into the GSK Green Chemistry Guide.

Launched in 2000, the GSK Green Chemistry Guide is a comprehensive site that provides guidance to GSK scientists and engineers on applying Green Chemistry concepts that will enable more efficient use of resources, reduce environment, health and safety impacts and minimize costs. It also contains a Technology section that provides both a methodology for ranking (Jimenez-Gonzalez et al., 2001, 2002) and the actual ranking of commonly used technologies against newer alternative technologies. Some of the contents of this module are shown in Figure 8.25.

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